Update Nov 2024:
Bite is now placed on the separate claws
MANDATORY MODS:
Viral Quills - spreads AOE viral procs and minor damage
Martyr Symbiosis - sacrifices itself to save you. [Primed Pack Leader] can prevent it from sacrificing itself and effectively byapssing the cooldown. You can then immediately revive it using Momentous Bond/Tenacious Bond
Fetch - mandatory vacuum
OPTIONAL MODS:
Resourceful Retriever - bonus loot
Momentous Bond - helps revive pet quicker, reduces 60s revive timer by 18s per eximus kill meaning getting three eximus kills basically fully revives. Flexible for [Panzer Devolution] (which locks you to 30s reviving time and prevents pet from being manuall revived, but allows more consistent uptime for Reinforced Bond + Tenacious Bond).
Synth deconstruct - OPTIONAL for mass producing health orbs, as any enemy touched by [Viral Quills] has a 25% chance to drop health orb. also gives holster reload bonus.
[Primed Pack Leader]: OPTIONAL if you are using a melee, since this gives overguard which keeps the pet alive more foten
Primed Animal Instinct is OPTIONAL since you now get universal radar, but loot radar is still useful
Tenacious Bond - gives free 1.2x flat crit damage to your weapons. Headshots also reduce revive timer by 3s.
Tek Assault - 60% chance to not die, OPTIONAL mod
Seismic Bond - OPTIONAL, but gives 30% bonus Ability Efficiency on warframes with "CHANNELLING ABILITIES" as [Viral Quills] deals damage. Note that the game has a VERY generous definition for channeling abilities as nearly every frame has an ability that seems to count. See Arcane Intention wiki page for a full list: https://warframe.fandom.com/wiki/Arcane_Intention
Hunter Recovery - optional mod for free healing. Viral quills constantly heals your health while active since it deals damage.
Calculated Redirection + Reinforced Bond - bonus 60% fire rate
Tandem bond - good on frames requiring melee combo eg [Baruuk], [Gara], [Khora], [Atlas]. [Viral Quills] count as an extra 3 melee combo per spore, meaning Panzer attacking gains up to 18 combo per enemy hit (assuming up to 6 spores). You can reach x12 combo in 10 seconds if you add grouping.
Mystic Bond - allows free casts on frames that don't use brief respite for shield gating, and viral quills helps trigger mystic bond
Loyal Companion - minor survivability boost
Medi pet kit - reduces revive timer if you don't use [Panzer Devolution]